Consultant Physician of Department of Internal Medicine of B & B Hospital, Lalitpur, Nepal (June 2009 till date)
Practising Physician Private practice Physcian in Banepa (Sept 1998 – April 1999)
Physician: Scheer Memorial Hospital, Banepa (Nov 1996 –Aug 1998)
Academic Qualifications:
MD Internal Medicine , Patna Medical College & Hospital Patna University, India (1993 – 96)
DTM&H School of Tropical Medicine, Calcutta University, India (1992 – 93)
MBBS, The Medical College, Calcutta University, India (1985 – 90)
Academic Experiences:
Clinical Tutor of FCPS in Internal Medicine
Associate professor of Internal Medicine, Kathmandu University School of Medical Sciences
Program Director of Fellowship in Adult Critical Care (FACC)
Organisational Achievements and Associations:
Founding member of Nepalese Society of Critical Care Medicine
Past President of Nepalese Society of Critical Care Medicine
Past Executive Member of Society of Internal Medicine of Nepal
Active member of
Nepal Medical Association (NMA)
Society of Internal Medicine of Nepal (SIMON)
Society of Gastroenterology of Nepal
Nepalese Society of Critical Care Medicine (NSCCM)
Indian Society of Critical Care Medicine
Chairperson of Antibiotic Policy committee to draft Antimicrobial Stewardship Program of B&B Hospital (2016-2017; first edition)
Chairperson of Antibiotic Policy committee to draft Antimicrobial Stewardship Program of B&B Hospital (2025-2026; second edition)
Scientific committee Chair of third International Conference of NSCCM (2018)
Publications and Research:
Principle Investigator of B and B ICU centre for Mega-ROX trial (an ongoing multicentre, multinational, randomized, parallel group, registry-embedded clinical trial)
Young P, Bellomo R, Al-Fares A, Antognini D, Arabi Y, Ashraf M, Bagshaw S, Brown A, Buabbas S, Campbell L, Chen J, Freebairn R, Fujii T, Hasan M, Jain A, Lai N, Lakhey S, Partlin M, Marment S, Lamontagne F. (2025). Mean arterial pressure targets in intensive care unit patients receiving noradrenaline: An international survey. Critical Care and Resuscitation. 27. 100095. 10.1016/j.ccrj.2024.12.001.
Bhusal S, Amatya I, Paudel S, Luitel S, Thakur A, Gauli B, Paneru H, Khanal K, Rajbanshi L, Shrestha P, Tiwari P, Koirala S, Lakhey S, Adhikari S, Shrestha S, Acharya S, Khanal S, Shrestha R, Bajaracharya T, Aryal D. (2025). Clinical Characteristics and Outcomes of Surgical Patients Admitted to Intensive Care Units. Wellcome Open Research. 10. 199. 10.12688/wellcomeopenres.23478.1.
Neupane M, Bhusal S, Amatya I, Luitel S, Paudel S, Shakya R, Thakur A, Gauli B, Paneru H, Khanal K, Rajbanshi L, Shrestha P, Tiwari P, Koirala S, Lakhey S, Adhikari S, Shrestha S, Acharya S, Khanal S, Aryal D. (2024). Empiric gram-negative antibiotics usage among critically ill patients across 13 ICUs of Nepal: A retrospective cohort study. Wellcome Open Research. 9. 573. 10.12688/wellcomeopenres.22948.2.
KC S, Gooden T, Aryal D, Koirala K, Luitel S, Haniffa R, Beane A, Nepal R, Khanal S, Paneru H, Shreshta S, Lakhey S, Amatya S, Thapa K, Maharjan R, Kafle R, Bashyal A, Shrestha R, Khadka D, Dullewe N. (2024). The burden of anxiety, depression, and stress, along with the prevalence of symptoms of PTSD, and perceptions of the drivers of psychological harms, as perceived by doctors and nurses working in ICUs in Nepal during the COVID-19 pandemic, a mixed method evaluation. BMC Health Services Research. 24. 10.1186/s12913-024-10724-7.
Aryal D, Thakur A, Gauli B, Paneru H, Koirala K, Khanal K, Rajbanshi L, Hirachan N, Shrestha P, Tiwari P, Shrestha R, Dhakal R, Gami R, Koirala S, Lakhey S, Adhikari S, Luitel S, Shrestha S, Acharya S, Haniffa R. (2023). Epidemiology of critically ill patients in intensive care units in Nepal: a retrospective observational study. Wellcome Open Research. 8. 180. 10.12688/wellcomeopenres.19127.1.
Lakhey, S. (2024). Is it time to integrate treatable traits into the syndromic definition of ARDS to personalize care? Journal of Nepalese Society of Critical Care Medicine, 2(3), 1–3.
Lakhey S, Suwal S, Singh SJ, Thapa S, Ranjit PS. Hydrocortisone, Vitamin C, and Thiamine for Treatment of Sepsis and Septic Shock: A Single Centre Retrospective Comparative Study. BBMed, 2020, 1:13-20.
Paneru HR, Aryal D, Shrestha GS, Kafle MP, Koirala S, Bajracharya T, Acharya SP, Adhikari S, Joshi LN, Lakhey S. Interim Intensive Care Unit protocol for the care of patients with Covid 19. Prepared by Nepalese Society of Critical Care Medicine. 6th Sept 2020.
Shrestha GS, Paneru HR, Acharya SP, Shrestha SK, Sigdel MR, Tiwari S, Yadav BK, Rijal B, Karki L, Neupane Y, Thapa N, Lakhey S. Preparedness for Coronavirus Disease in Hospitals of Nepal: A Nationwide Survey. JNMA J Nepal Med Assoc. 2020 Apr 30;58(224):248-251. doi: 10.31729/jnma.4941. PMID: 32417862; PMCID: PMC7580458.
Bajracharya M,Dhungana I, Ranjit PS, Lakhey S. Hemichorea-Hemiballismus as a Complication of Hyperosmolar Hyperglycemic State: A case report. BBMed 2017,1:173-176.
Adhikari J,Mishra DK, Lakhey S. Paratyphoid a Fever with Myocarditis and Nephritis: A Case Report. BBMed 2017,1:177-180
Lakhey S, Shrestha R, Thapa S, Tuladhar S. Scenario of Acute Respiratory Distress Syndrome in a Tertiary Care Centre. JNMA 2010; 49(178): 129-132.
Lakhey S, Karki B, Shrestha B, Shakya S, Pandey S B. Sepsis: A Private Hospital Experience in Nepal. JIOM 2006; 28:1, 12-15.
Lakhey S, Pandey S B. Characteristics of reflux oesophagitis in Nepalese population as determined by Los Angeles Classification. JIOM 2004; 26:1, 15-17.
Lakhey S, Shrestha R L, Shrestha B K. Autonomic Dysreflexia: A case report. J Neuroscience 2004; 1: 55-56.
Peer reviewer for JNMA (Journal of Nepal Medical Association)
Peer reviewer for KUMJ (Kathmandu University Medical Journal)
Editorial Member of B and B Medical Journal Editorial Board (2020-2021)
Presentations:
Heterogeneity and Heterogenous Treatment effect in ARDS: Is Precision Medicine in the offing? Plenary Talk in 6th International Conference of Nepalese Society of Critical Care Medicine (November 15th-16th 2024, Sauraha, Chitwan)
ARDS: In search of Holy Grail. Invited Lecture in 15th International Conference of Society of Internal Medicine of Nepal (December 1-2, 2023, Kathmandu)
Implementing Survival Sepsis Campaign Guidelines: Protocol versus Pragmatism. Keynote Speech, 5th National Conference of SIMON, 14th-15th October 2022.
Antimicrobials, Fluids and Vasopressors - Should metabolic resuscitation be the fourth dimension in the management of sepsis and septic shock. Invited Lecture in Birgunj CME on 7th June 2019.
IV Fluids and Vasopressors in Sepsis: The evidence behind the guidelines and the future directions. Invited Lecture in Third International Conference of NSCCM, 16th – 17th November 2018.
A Pragmatic Approach to Surviving Sepsis Campaign Guidelines 2017. Invited Lecture in Thirteenth International Conference of SIMON, 4th – 6th May 2017.
Sepsis and ARDS: Glimpses of the Unholy Alliance (2016). Plenary Lecture Second International Conference of NSCCM, 26th Nov 2016.
Sepsis 3.0 - What does it mean?Invited Lecture in SIMON CME 21st May 2016
Sepsis Update 2015: Redefining Sepsis, and IV Fluids in Sepsis - The Dilemma. Invited Lecture in Twelfth International Conference of SIMON 23rd - 25th April 2015.
What’s new in management of septic shock? Invited Lecture in (BB CME)
SEPTIC SHOCK: Management & controversies. Keynote Lecture in First National conference of Nepalese Society of Critical Care Medicine (NSCCM), & First Congress of Association of SAARC Critical Care Societies (ASAARCCCS). 15th November 2014, Saturday, Kathmandu, Nepal.
Insulin therapy in critically ill patients. Invited Lecture in Diabetes Conclave 2014, Sept 12th, 2014 Kathmandu, Nepal.
Culture sensitivity pattern of pathogens of ICU in Nepal and its impact on choice of initial empiric antibiotic therapy. Invited Lecture in CRITICARE 2014, 14-18th Feb 2014, Jaipur India.
The Surviving Sepsis Campaign Guidelines for management of severe sepsis and septic shock, 2012: An Update. Invited Lecture in The Conference of the Society of Internal Medicine of Nepal (SIMON), April 5-6, 2013, Kathmandu, Nepal.
Surviving Sepsis Campaign Guidelines: Is the road less travelled? Invited Lecture in CME presentation of Nepalese Society of Critical Care Medicine. June 1st, 2012, Kathmandu, Nepal
Characteristics of reflux esophagitis in Nepalese population as determined by Los Angeles Classification. Paper presentation in ANEMECON-22, 2-4th March 2005, Kathmandu, Nepal.
A Case Report on Ocular Toxoplasmosis. Paper presentation at Nepal Medical Association Conference in January 1997 at Nepalgunj, Nepal.
Testimonials:
From Prof Ira Bailie, MD, FACS, Medical Director Scheer Memorial Hospital, Banepa & Professor of Surgery, Loma Linda University School of Medicine California, USA. August 1998.
From Prof I B Sinha, Dept of General Medicine, Patna Medical College Hospital, Patna, India. July 1996.